PLEASE NOTE: If you have active herpes, chicken pox, or shingles DO NOT USE L-arginine.
CAUTION: About one percent of people (one out of a hundred) using andrographis report allergic reactions. Primarily the reaction shows as a rather severe skin rash; essentially hives. This will resolve if you stop taking the herb, though it might take a week or so. Anti-inflammatories such as cortisone creams are not necessary; it will clear up on its own. Please pay attention to any skin reactions you might have to the herb and discontinue it if you have a reaction. If you are one of the very few that does experience a reaction, you can continue the rest of the herbs in the core protocol, simply deleting andrographis.
NOTE: Two people have reported rises in liver enzyme levels on the protocol. The cause is unknown. Andrographis, knotweed, and smilax are all herbs used historically for liver problems, all are specific for healing liver disease. That increases in liver enzymes has occurred is odd since the herbs are specific for lowering those levels; they are good liver protector herbs and have been traditionally used for liver disease for millennia. This reaction is very unusual and the only reason I can find for it is personal reactivity to one of the herbs. The best thing to do if you do experience increases in liver enzymes is to stop the protocol and then reintroduce the herbs one at a time to see which one is the problem.
NOTE: A few people have experienced loss of taste on the protocol. The herb responsible for this has not been identified but I think it is probably the knotweed as that plant does cause, sometimes, alterations in taste. It can take up to 3 months to correct itself after the herb has been discontinued.